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20

Compounds

Cat No. Product Name Synonyms Targets
TN3651 Cichoriin Others
Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats.
T9614 MERS-CoV-IN-1 SARS-CoV
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS).
T3S1447 Arteannuin B SARS-CoV , Ferroptosis
1. Arteannuin B has potent antimalarial activity.
T40660 Kansuinine B IL Receptor , SARS-CoV
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research.
T9109 SSAA09E2 RAAS , SARS-CoV
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).
T8419 XP-59 SARS-CoV
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
TQ0180 Chebulagic acid SARS-CoV , Influenza Virus , Lipoxygenase , COX
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
T9458 PF-00835231 SARS-CoV
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i...
TQ0302 Thapsigargin Apoptosis , SARS-CoV , Calcium Channel
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ...
T40276 GS-621763 SARS-CoV
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.
T7872 Monolaurin Others
Monolaurin is a surfactant and emulsifer found in coconut oil. It inhibitis growth of Staphylococcus, Streptococcus, Gardnerella, Candida, and Haemophilus, and decreases production of pro-inflammatory cytokines.
T9351 Nirmatrelvir SARS-CoV
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
T9672 GRL-0496 SARS-CoV
GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM.
T21727 Ivermectin B1a SARS-CoV , Parasite
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
T2869 Emodin Frangula emodin SARS-CoV , Casein Kinase , Autophagy
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.
T9618 HeE1-2Tyr SARS-CoV
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro.
T1134 Clofoctol Antibacterial , Antibiotic
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections.
T11464 GRL0617 SARS-CoV , DUB
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
T1303 Auranofin SKF-39162 Others , SARS-CoV , Antibacterial
Auranofin (SKF-39162) is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness.
T8371 ML188 Virus Protease , SARS-CoV
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
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