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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN3651 | Cichoriin | Others | |
Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats. | |||
T9614 | MERS-CoV-IN-1 | SARS-CoV | |
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS). | |||
T3S1447 | Arteannuin B | SARS-CoV , Ferroptosis | |
1. Arteannuin B has potent antimalarial activity. | |||
T40660 | Kansuinine B | IL Receptor , SARS-CoV | |
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research. | |||
T9109 | SSAA09E2 | RAAS , SARS-CoV | |
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2). | |||
T8419 | XP-59 | SARS-CoV | |
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM). | |||
TQ0180 | Chebulagic acid | SARS-CoV , Influenza Virus , Lipoxygenase , COX | |
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor. | |||
T9458 | PF-00835231 | SARS-CoV | |
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i... | |||
TQ0302 | Thapsigargin | Apoptosis , SARS-CoV , Calcium Channel | |
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ... | |||
T40276 | GS-621763 | SARS-CoV | |
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis. | |||
T7872 | Monolaurin | Others | |
Monolaurin is a surfactant and emulsifer found in coconut oil. It inhibitis growth of Staphylococcus, Streptococcus, Gardnerella, Candida, and Haemophilus, and decreases production of pro-inflammatory cytokines. | |||
T9351 | Nirmatrelvir | SARS-CoV | |
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) . | |||
T9672 | GRL-0496 | SARS-CoV | |
GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM. | |||
T21727 | Ivermectin B1a | SARS-CoV , Parasite | |
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a. | |||
T2869 | Emodin | Frangula emodin | SARS-CoV , Casein Kinase , Autophagy |
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways. | |||
T9618 | HeE1-2Tyr | SARS-CoV | |
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro. | |||
T1134 | Clofoctol | Antibacterial , Antibiotic | |
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections. | |||
T11464 | GRL0617 | SARS-CoV , DUB | |
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM). | |||
T1303 | Auranofin | SKF-39162 | Others , SARS-CoV , Antibacterial |
Auranofin (SKF-39162) is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness. | |||
T8371 | ML188 | Virus Protease , SARS-CoV | |
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity. |